Essay about Breast Cancer - 836 Words

Breast cancer is one of the most widespread cancers among women worldwide. In the US, it is the most common, and the leading cause of cancer related deaths among women between 45 – 64 years of age (Clegg et al., 2002; Ward et al., 2008). Early detection and improved treatment procedures have resulted in gradual decline in the number of deaths caused by the disease since 1990. Nevertheless, in 2009, the estimated death toll for the disease was 40,170 (American Cancer Society, 2009). The gravity of the disease therefore demands further research towards its early diagnosis, and for evaluating the prognosis of its course. Breast cancer is a heterogeneous disease characterized by the complex interplay of molecular, genetic and†¦show more content†¦The principal mechanism leading to pain and inflammation is the arachidonic acid (AA) pathway. AA is typically bound to the membrane phospholipids and is released by a group of enzymes known as the phospholipases A2’s. AA acts as the precursor of the group of bioactive lipids collectively known as the eisosanoids. There have been several reports that AA and the eicosanoids are intimately linked to cancer biology (Markaverich et al., 2007; Nie et al., 2001; Pan et al., 2008; Sveinbjornsson et al., 2008). The downstream enzymatic pathways of AA, the cycloxygenases (COX) and the lipoxygenase (LOX) pathways, are responsible for the synthesis of the eicosanoids from AA. Elevated levels of the COX-2 protein have been reported in archived breast cancer tissue, and studies indicate that the overexpression of COX-2 is sufficient to induce mammary tumor formation in transgenic mice (Denkert et al., 2004; Liu et al., 2001). Human cancerous breast tissue indicates 3- to 30-fold higher 12-LO mRNA when compared to the normal breast tissue (Ding et al., 2003; Natarajan et al., 1997). There is sufficient evidence that the products of the COX and LOX enzymatic pathways, the eicosanoids, such as the prostaglandin (PG) PGE2 andShow MoreRelatedBreast Cancer And Cancer Prevention2347 Words   |  10 Pages INTRODUCTION Statistics indicate that breast cancer-related complications are among the top causes of death among women for over 23% of all women’s deaths in the world (Donepudi et al., 2014). The great cases of breast cancer are attributed to lack of information on and hard data on the disease, especially on early diagnosis and treatment options. In America, breast cancer is among the top causes of cancer-related deaths, and the mortality rate is relatively high as compared to the neighboring countriesRead MoreThe For Breast Cancer Action1612 Words   |  7 Pagesintention to give some part of the profit towards breast cancer causes. Ironically, the money made from this marketing will often not significantly benefit somebody with breast cancer. The pink ribbon was originally created by the Susan G Komen foundation yet anybody can use this symbol, because there is no intellectual copyright on it. Pinkwashing is term was first coined by the organization called breast cancer action, whose m ission is to â€Å"Breast Cancer Action’s mission is to achieve health justiceRead MoreBreast Cancer : Cancer And Cancer Essay1433 Words   |  6 PagesBreast cancer is a carcinoma that develops due to malignant cells in the breast tissue. Cancerous cells are more likely to produce in the milk-producing ducts and the glands, ductal carcinoma, but in rare cases, breast cancer can develop in the stromal, fatty, tissues or surrounding lymph nodes, especially in the underarm (Breast Cancer). For women, breast cancer is the most commonly diagnosed cancer and the 2nd leading cause of cancer death – behind skin cancer. While treatment or surgeries canRead MoreBreast Cancer : Cancer And Cancer1346 Words   |  6 Pagesinternational symbol for breast cancer support and awareness. Breast cancer knows neither racial boundaries nor age restrictions. Females of all ages and ethnicities can develop breast cancer and it is the leading most common cancer among women. Calling at tention to this often fatal disease is important by supporting its victims, families and friends of victims, as well as raising funds for breast cancer research. Though males are not immune from developing a breast cancer, for the purposes of thisRead MoreBreast Cancer : Cancer And Cancer946 Words   |  4 PagesSkylar Steinman Period 6 Ms. Jobsz 12 February , 2016 Breast Cancer It is commonly known that Breast Cancer is one of the most insidious diseases that mankind has had to deal with. With the discovery of the BRCA1( BReast Cancer gene one) and BRCA2 (BReast Cancer gene two) genes, breast cancer can be detected with a great amount of certainty on a genetic level in some women and men. 40,000 women and men die of breast cancer each year. Knowing this it is very important to try to detect the mutationRead MoreBreast Cancer : Cancer And Cancer1530 Words   |  7 Pagesâ€Å"Cancer† is the name for a group of diseases that start in the body at the cellular level. Even though there are many different kinds of cancer, they all begin with abnormal cell growth with the potential to invade or spread to other parts of the body. These abnormal cells lump together to form a mass of tissue or â€Å"malignant tumor†. Malignant means that it can spread to other parts of the body or Metastasize . If the breast is the original location of the cancer gr owth or malignant tumor, the tumorRead MoreBreast Cancer : Cancer And Cancer Essay1741 Words   |  7 Pages Internationally, breast cancer is the most commonly diagnosed cancer and the leading cause of cancer related death amongst women. (CITE) Each year an estimated 1.7 million new cases are diagnosed worldwide, and more than 500,000 women will die of the disease. (CITE) According to (CITE), somewhere in the world one woman is diagnosed with breast cancer every 19 seconds and more than three women die of breast cancer every five minutes worldwide. (CITE) Breast cancer is a heterogeneous condition thatRead MoreBreast Cancer : Cancer And Cancer1372 Words   |  6 PagesBreast Cancer Disease Overview Breast cancer is a disease in which certain cells in the breast become abnormal and multiply uncontrollably to form a tumor. Breast cancer is the second most commonly diagnosed cancer in women. (Only skin cancer is more common.) About one in eight women in the United States will develop invasive breast cancer in her lifetime. Researchers estimate that more than 230,000 new cases of invasive breast cancer will be diagnosed in U.S. women in 2015. Cancers occur when aRead MoreBreast Cancer : Cancer And Cancer1471 Words   |  6 PagesBreast cancer Introduction to Breast cancer Breast cancer is one of the most common forms of cancer only surpassed by lung cancer. It involves a cancerous tumour located inside the breast but spreads if treatment is not administered. (Evert et al 2011) Breast cancer can be treated if diagnosed in its early stages but becomes progressively more difficult upon reaching more advancing malignant stages. Breast cancer can be confused with being a female only disease however both sexes suffer. AccordingRead MoreBreast Cancer : Cancer And Cancer1921 Words   |  8 PagesIntroduction Cancer is a term that every individual on this planet wants to avoid hearing when they go to their yearly check up at the doctors. However, as person ages, they are prone to develop some sort of sickness and most of the time, they could develop cancer of some sort. For this research paper, I am going to go over breast cancer. Breast cancer is a well-known type of cancer with awareness events going on to support both women and men who has breast cancer. According to American Cancer Society